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Case Report
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Korean J Med. 2015;88(6):737-741. Published online June 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.6.737
- 강직성 척추염 환자에서 발생한 갑상선자극호르몬(TSH) 분비 뇌하수체 선종 1예
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박지혜1, 이승근1, 박은경1, 구동완1, 김보현1, 김인주1, 김근태2
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1부산대학교 의학전문대학원 내과학교실
2고신대학교 의과대학 내과학교실
- A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
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Ji-Heh Park1, Seung-Geun Lee1, Eun-Kyoung Park1, Dong-Wan Koo1, Bo-Hyun Kim1, In-Joo Kim1, Geun-Tae Kim2
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1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
2Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
- Corresponding author: Seung-Geun Lee ,Tel: +82-51-240-7580, Fax: +82-51-241-7581, Email: sglee@pnuh.co.kr
- Received: October 9, 2014; Revised: November 6, 2014 Accepted: December 1, 2014.
- 저자들은 강직성 척추염을 진단받고 외래에서 추적관찰 중인 환자에서 동반된 갑상선자극호르몬 분비 뇌하수체 선종을 TRH 자극검사, 갑상선자극호르몬 α‐아단위 측정 및 자기공명영상으로 진단하고 수술로 치료하여서 호전된 드문 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 두 질환과의 상호 연관성에 대해서는 추가적인 연구가 필요할 것으로 판단된다.
߽ɾ :뇌하수체샘종; 갑상샘자극호르몬; 강직척추염
- Abstract
- A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH α-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.
Keywords :Pituitary neoplasms, Thyrotropin, Spondylitis, Ankylosing
