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Special Review
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Korean J Med. 2015;88(6):643-646. Published online June 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.6.643
- 특수한 경우의 C형 간염 치료: 간경변증
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곽금연
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성균관대학교 의과대학 삼성서울병원 내과
- Treatment of Hepatitis C in Special Conditions: Liver Cirrhosis
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Geum-Youn Gwak
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Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
- Corresponding author: Geum-Youn Gwak ,Tel: +82-2-3410-3409, Fax: +82-2-3410-6983, Email: gy.gwak@samsung.com
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߽ɾ :C형 간염; 간경변증; SVR; 항바이러스 치료
- Abstract
- Acquiring a sustained virological response (SVR) in patients with cirrhosis or advanced hepatic fibrosis reduces liver disease-related mortality and the incidence of hepatocellular carcinoma. However, the SVR rate of the current standard of care, which is combination therapy with peg-interferon-alpha and ribavirin, is significantly lower, and treatment-related complications occur more frequently in patients with cirrhosis. Thus, antiviral treatment should be individualized in this population. This review high-lights the issues associated with anti-hepatitis C virus treatment in patients with compensated and decompensated cirrhosis.
Keywords :Hepatitis C, Cirrhosis, SVR, Antiviral therapy
