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Case Report
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Korean J Med. 2014;87(2):219-223. Published online August 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.2.219
- 단풍마 복용 후 발생한 세뇨간질성 신염
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전지민1, 박용기1, 전미영2
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1동래봉생병원 신장내과
2메리놀병원 병리과
- Dioscorea Quinqueloba-Induced Tubulointerstitial Nephritis
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Ji Min Jeon1, Yong Ki Park1, Mi Young Jeon2
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1Department of Internal Medicine, Dongrae Bong Seng Hospital, Busan, Korea
2Department of Pathology, Maryknoll Medical Center, Busan, Korea
- Corresponding author: Ji Min Jeon ,Tel: +82-51-520-5622, Fax: +82-51-520-5639, Email: 59356815@hanmail.net
- Received: November 11, 2013; Revised: December 3, 2013 Accepted: January 7, 2014.
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߽ɾ :단풍마; 세뇨간질성 신염; 급성신부전
- Abstract
- Drug-induced tubulointerstitial nephritis is one cause of acute kidney injury. Although traditional remedies have been widely used in South Korea, Dioscorea quinqueloba-induced tubulointerstitial nephritis has not been reported in the general population. A 72-year-old male patient was transferred to our hospital with pulmonary edema, oliguria, decreased mentality, severe generalized edema after taking D. quinqueloba 25 days ago. His initial lab findings showed a blood urea nitrogen level of 43.4 mg/dL, a creatinine level of 5.3 mg/dL. Urinalysis revealed SG (1.015), blood (many), protein (++) and WBC (0-3/HPF). Kidney biopsy demonstrated severe mononuclear cell infiltration into the renal interstitium with mild tubular atrophy. Aggressive renal replacement therapy and supportive care resulted in gradual restoration of his renal function. This case implies that D.
Keywords :Dioscorea quinqueloba, Tubulointerstitial nephritis, Acute kidney injury
