The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2010;78(6):737-740.
Helicobacter pylori 제균 요법과 proton pump inhibitor 치료 후 호전된 Ménétrier’s씨 병 1예
윤지훈, 박승제, 최재원, 최성원, 박승근, 박희욱, 김혜숙
Division of Allergy, Asthma and Clinical Immunology, Department of Internal Medicine, Chonnnam National University Medical School, Gwangju, Korea
A case of improved Ménétrier’s disease after the eradication of Helicobacter pylori and treatment with a proton pump inhibitor
Ji Hoon Yoon, Seung Jei Park, Jae Won Choi, Sung Won Choi, Seung Keun Park, Hee Ug Park, Hye Sook Kim
전남대학교 의과대학 알레르기내과


Abstract
Ménétrier’s disease is a protein-losing hypertrophic gastropathy characterized by diffuse tremendous thickening of the gastric wall caused by excessive proliferation of the mucosa. Although the cause of Ménétrier’s disease is unknown, an association with Helicobacter pylori has been reported. A 42-year-old man was hospitalized for the evaluation of progressive body weight loss and indigestion for 6 months, with recently aggravated epigastric discomfort. Gastroscopy revealed prominent mucosal folds in the body and fundus. The histological findings revealed gastritis with erosions and foveolar hyperplasia. After eradicating the Helicobacter pylori and treatment with a proton pump inhibitor, clinical and endoscopic resolution ensued. (Korean J Med 78:737-740, 2010)

Keywords :Mé, né, trier’s disease, Helicobacter pylori
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