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Original Article
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Korean J Med. 2009;77(5):1183-1187.
- 한랭글로불린혈증에서 동반된 기질화 폐렴 1예
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김연재·김상헌·김태형·윤호주·신동호·박성수·손장원, , , , , ,
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- A case of organizing pneumonia with cryoglobulinemia
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Yeon Jae Kim, Sang Heon Kim, Tae Hyung Kim, Ho Joo Yun, .Dong Ho Shin, Sung Soo Park, Jang Won Sohn
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- Abstract
- Cryoglobulinemia refers to the presence of serum polyclonal immunoglobulins that precipitate reversibly at cold temperature.
Cryoglobulinemia can involve various organs, including the skin, liver, kidney, and lung. Although many diseases can lead to organizing
pneumonia, reports of organizing pneumonia with cryoglobulinemia (OPC) are rare. We treated a case of prolonged migrating
patchy lung infiltration combined with mixed cryoglobulinemia. A 75-year-old man was admitted with progressive dyspnea
and cough. The serological, clinical, and pathological findings confirmed the presence of mixed cryoglobulinemia. A chest radiograph
and computed tomography (CT) showed multiple patchy consolidations that did not resolve with empirical antibiotic
treatment. Additionally, his symptoms did not respond to antibiotics. The transbronchial lung biopsy showed organizing pneumonia,
so steroid treatment was started, and the clinical symptoms and radiological findings improved. (Korean J Med 77:S1183-
S1187, 2009)
Keywords :Organizing pneumonia, Cryoglobulinemia
