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Original Article
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Korean J Med. 2009;76(1):15-21.
- 광범위한 간내 전이를 보인 전이성 신경내분비종양 3예
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박의주, 전성란, 김대용, 장재영, 김정훈, 진소영, 심찬섭
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- Three cases of extensive liver metastasis in neuroendocrine tumors
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Eui Ju Park, Seong Ran Jeon, Dae Yong Kim, Jae Young Jang, Jung Hoon Kim, So Young Jin, Chan Sup Shim
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- Abstract
- Malignant neuroendocrine tumors have the histological features of malignant tumors, and localized invasion and distant metastasis
can occur. After clinical presentation, patients with neuroendocrine tumors usually show rapid deterioration. The first case involved
a patient who underwent treatment for poorly differentiated adenocarcinoma of the lung. A percutaneous liver biopsy was
performed to look for diffuse infiltration of the tumor in the liver. As a result, the patient was diagnosed with large-cell neuroendocrine
carcinoma of the lung with diffuse liver metastasis. The other two patients presented with liver masses. Liver biopsies revealed
metastatic neuroendocrine tumors of the liver. In patients presenting with diffuse hepatic infiltration of a tumor, a neuroendocrine
tumor should be considered in the diagnosis, and immunohistochemical staining and further studies should be performed
to locate the origin of the tumor. We report three cases of neuroendocrine tumors with diffuse liver metastasis. (Korean J Med
76:S15-S21, 2009)
Keywords :Neuroendocrine tumor, Liver, Neoplasm metastasis
