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Original Article
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Korean J Med. 2009;76(6):752-757.
- IPSS 검사로 진단된 TSH 분비 뇌하수체 미세선종 1예
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성중경, 김은미, 남수민, 신영구, 정춘희, 황 금, 고장현
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- A TSH-secreting pituitary microadenoma diagnosed with inferior petrosal sinus sampling: Case report
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Joong Kyung Sung, Eun Mi Kim, Su Min Nam, Young Goo Shin, Choon Hee Chung, Kum Whang, Jang Hyun Koh
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- Abstract
- Thyroid stimulating hormone (TSH)-secreting pituitary adenomas are rare tumors of the pituitary gland and represent 1~2% of all pituitary adenomas. A TSH-secreting pituitary adenoma shows as a normal or elevated thyrotropin level in a hyperthyroid patient. We present a 32-year-old woman who was diagnosed with a TSH-secreting pituitary microadenoma. She had a high free T4, with a normal TSH and α-subunit. Bilateral inferior petrosal sinus sampling (IPSS) was done to confirm the α-subunit secreting adenoma, and the concentration of the α-subunit was high on the tumor side. The pituitary microadenoma was removed, and her TSH and free T4 levels decreased to normal. IPSS may help give an accurate diagnosis in the patient with a normal α-subunit.
Keywords :α-Subunit, Inferior petrosal sinus sampling, Pituitary microadenoma, TSH
