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Original Article
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Korean J Med. 2009;76(2):220-224.
- 알로퓨리놀 사용 후 발생한 진성 적혈구 감소증 1예
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이진호 &#; 허종훈 &#; 권경아 &#; 한대희 &#; 황종운 &#; 조 성 &#; 김성, , , , , ,
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- Allopurinol hypersensitivity syndrome and pure red cell aplasia associated with allopurinol treatment
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Jin Ho Lee, Jong Hun Heo, Kyung A Kwon, Dae Hui Han, Jong Woon Hwang, Seong Cho, Sung Rok Kim
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- Abstract
- Allopurinol is widely used to reduce serum uric acid levels and, generally, has mild side effects. Rarely, allopurinol
hypersensitivity syndrome occurs and this consists of severe systemic skin lesions, fever, reduced kidney and liver function, and
leukocytosis with eosinophilia. Extremely rarely, allopurinol-induced pure red cell aplasia is reported. We report a case of
allopurinol hypersensitivity syndrome and pure red cell aplasia following allopurinol therapy for eight weeks and the disease
response to steroid therapy in a patient with chronic renal insufficiency. (Korean J Med 76:220-224, 2009)
Keywords :Allopurinol, Pure red-cell aplasia
