The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2008;74(1):107-111.
증례 : 전신적 림프절 종대와 골 용해성 병변을 동반한 전립선암 1예
김지환, 이순일, 박건우, 김윤섭, 이호연, 공재환, 라성수
A case of prostate cancer with generalized lymphadenopathy and osteolytic bone metastases
Ji Hwan Kim, Soon Il Lee, Keon Woo Park Youn , Ho Youn Lee, Jae Hwan Kong, Sung Soo La ,
성균관 의과대학교 삼성서울병원 심혈관센터 순환기내과


Abstract
Prostatic cancers often metastasize to regional lymph nodes and bones by hematogenous or lymphangitic spread, but generalized lymphadenopathy is a very uncommon manifestation of prostatic cancer. A 69-year-old man presented with cough, sputum production, and cervical lymph node enlargement. On computed tomography (CT) of the chest and abdomen, lymphadenopathy of the left cervical, left supraclavicular, mediastinal, subcarinal, retroperitoneal and inguinal lymph nodes was noted. Osteolytic bone metastases of the thoracic and lumbar spine were also noted. Pelvic CT scan showed a low-density bulging mass on the left lobe of the prostate. Frequency was the only urinary symptom, and the patient’s plasma prostate-specific antigen (PSA) was markedly elevated. Excisional biopsy of left supraclavicular lymph node revealed metastatic prostate adenocarcinoma. We report this case along with a review of the literature.

Keywords :Prostate cancer, Lymphadenopathy

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