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Original Article
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Korean J Med. 2008;74(1):42-47.
- 증례 : 위선암과 동반된 신경내분비종양; 충돌종양과 혼합종양 동시 발생 1예
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최문영, 심윤수, 김인제, 정혜경, 신수연, 문일환, 이시내
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- A case of concurrent gastric neuroendocrine carcinoma and adenocarcinoma: composite tumor combined with collision tumor
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Moon Young Choi, Yun Su Sim, In Je Kim, Hye-Kyung Jung, Su Youn Shin, Il Hwan Moon, Si Nae Lee
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경희대학교 의과대학 순환기내과학교실
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- Abstract
- Concurrent gastric neuroendocrine carcinoma and adenocarcinoma is very rare and usually is diagnosed at postoperative state because gross differentiation of the mixture of two tumors is difficult. We experienced a case in which the tumor seemed to be gastric cancer on gastroduodenoscopy and was diagnosed as undifferentiated adenocarcinoma by endoscopic biopsy. However, postoperatively it was revealed as adenocarcinoma mixed with collision and composite types of neuroendocrine tumors based on histologic examination and immunohistochemistry. The prognosis of concurrent gastric neuroendocrine carcinoma and adenocarcinoma is determined by malignant potential of the larger portion of tumor. Generally prognosis of neuroendocrine tumor is better than that of the gastric adenocarcinoma. However, as in our case, if the poorly differentiated neuroendocrine carcinoma occupies the large portion of the tumor, the prognosis is poorer than that of solitary gastric adenocarcinoma. Therefore, it may be needed closer postoperative follow up.
Keywords :Neuroendocrine tumor, Adenocarcinoma, Stomach
