The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2008;74(4):435-440.
증례 : 유방 침범을 동반한 원발성 자궁경부림프종 1예
김내유, 조인성, 공수정, 이미란, 박미자, 임춘화, 이정애
A case of primary malignant uterine cervical Non-Hodgkin’s lymphoma with breast involvement
Nae Yu Kim, In Sung Cho, Soo Jung Gong, Mee Ran Lee, Mee Ja Park, Chun Hwa Ihm, Jung-Ae Lee
성균관대학교 의과대학 삼성서울병원 심장혈관센터 순환기내과


Abstract
Primary lymphoma arising from the uterine cervix has been rarely encountered, and breast involvement is rare because of the relative paucity of lymphoid tissue in the breast. A 32-year-old woman with a primary malignant lymphoma of the uterine cervix and breast involvement is reported. The patient presented with post-coital vaginal bleeding, and punch biopsy of the cervix revealed the diffuse large B cell type of malignant lymphoma. PET-scan was done for staging, and abnormal FDP uptakes were detected in a uterine cervical mass and breast nodule. Ultrasonography-guided needle biopsy was done for the breast mass, and 2 biopsied nodules revealed fibroadenoma and diffuse large B cell lymphoma. The patient (Ann Arbor stage IV) was treated with 6 cycles of combination chemotherapy with CHOP plus rituximab. The patient went into complete remission. Thereafter, 4500cGy pelvic irradiation was done for adjuvant therapy.

Keywords :Primary uterine cervical lymphoma, Breast involvement
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