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Original Article
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Korean J Med. 2007;73(3):935-940.
- 증례 : 간에 발생한 원발성 신경내분비 암종 1예
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신재욱&#;장기택&#;김종규&#;오성욱&#;이유지&#;조수진&#;최성호, , , , , ,
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- A case of primary neuroendocrine carcinoma of the liver
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Jae Uk Shin, Kee-Taek Jang, Jong Kyu Kim, Sung Ook Oh, Yu Ji Lee, Soo Jin Cho, Seong Ho Choi
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경희대학교 의과대학 순환기내과학교실
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- Abstract
- We report a case of primary hepatic neuroendocrine carcinoma in a 74-year-old woman. The patient had a large mass
measuring 10 cm in its greatest diameter in the liver. The preoperative biopsy diagnosis was a poorly differentiated
cholangiocarcinoma, but the final diagnosis was a primary neuroendocrine carcinoma of the liver. Microscopically, the
tumor cells showed small oval-shaped nuclei with a trabecular arrangement and rosette-like features. In the
immunohistochemical staining, the tumor cells showed positive immunoreactivity for chromogranin A and synaptophysin.
The patient also had metastases in the gallbladder and in one pericholedochal lymph node. The systemic evaluation did
not reveal any other primary lesion of neuroendocrine carcinoma. After 3 months of follow-up, there was no evidence
of recurrence or metastasis in the radiologic examination.(Korean J Med 73:S935-S940, 2007)
Keywords :Neuroendocrine carcinoma, Liver
