The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2007;73(2):200-205.
증례 : Sildenafil 치료로 성공적으로 출산한 문맥성 폐동맥고혈압(Portopulmonary Hypertension) 1예
민희석, 장혁재, 조영석, 연태진, 정우영, 채인호, 최동주
Portopulmonary hypertension in pregnancy: Treatment with sildenafil
Hee-Suk Min, Hyuk-Jae Chang, Yong-Seok Cho, Tae-Jin Youn, Woo-Young Chung, In-Ho Chae, Dong-Ju Choi
경희대학교 의과대학 순환기내과학교실


Abstract
The mortality of pulmonary hypertension that complicates pregnancy is very high. The increased pulmonary vascular resistance combined with the normal physiological changes of pregnancy and delivery is difficult to manage. We describe here the case of a pregnant woman who presented with severe portopulmonary hypertension. A 30-yr-old woman presented with dyspnea at 8 weeks of pregnancy. The mean pulmonary artery pressures (PAP), as measured from a pulmonary artery catheter at 20 weeks gestation, were 71 mmHg. Sildenafil was used to reduce the PAP for 4 months. She responded to sildenafil therapy and successfully completed her pregnancy.(Korean J Med 73:200-205, 2007)

Keywords :Pulmonary hypertension, Portal hypertension, Pregnancy

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