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Original Article
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Korean J Med. 2006;71(5):551-557.
- 증례:쇼그렌 증후군에 병발한 다발성 위유암종 1예
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조근종, , , , , ,
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- A case of multiple gastric carcinoid tumors associated with Sjogren’s syndrome
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Keun Jong Cho, Jin Soo Kim, Chang Whan Kim, Jae Kwang Kim, Sok Won Han, In Sik Chung, Jean A Kim
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고려대학교 의과대학 내과학교실
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- Abstract
- Carcinoid tumors are rare endocrine neoplasms arising from the enterochromaffin or enterochromaffinlike
cells. Gastric carcinoids associated with autoimmune atrophic gastritis and hypergastrinemia, are
usually multiple and the prognosis are better compared to solotary lesions with out hypergastrinemia.
Gastric carcinoids are commonly associated with other endocrine disorders or tumors, but any
associations with autoimmune disorders other than autoimmune atrophic gastritis have rarely been
reported. Sjogren's syndrome is an autoimmune exocrinopathy that primarily affects the salivary
glands, but it can also involve almost any other part of the gut. The most common form of
gastrointestinal involvement in Sjogren's syndrome is chronic atrophic gastritis, which can lead to
hypergastrinemia and the subsequent development of carcinoid. However, gastric carcinoid tumor
associated with Sjogren's syndrome has not yet been reported on. To the best of our knowledge, this
is the first such case in the world. We report on this case along with review of the related
literature.(Korean J Med 71:551-557, 2006)
Key Words : Carcinoid tumor, Sjogren's syndrome
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