The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;70(2):352-357.
증례 : 쇼그렌 증후군에 동반된 유육종증 1예
강병수
Case Reports : A case of sarcoidosis with primary Sjogren's syndrome
Byoung Soo Kang
한림의대 한강성심병원 내과


Abstract
A 40 year old woman with a past history of Sjogren's syndrome presented with complaints of general weakness and weight loss. Abdomen CT revealed wall thickening in hepatic flexure of colon. FDG positron emission tomography (PET) showed hypermetabolic lesion in ascending colon. She was diagnosed as having colon cancer and underwent right hemicolectomy. Pathologic finding showed non-caseating granuloma consistent with sarcoidosis. The same granulomatous lesion was found in the lung and serum angiotensin converting enzyme (ACE) level was elevated. She was diagnosed as having sarcoidosis with primary Sjogren's syndrome. She received oral steroid therapy. Her general condition improved and serum ACE level was decreased. Occasionally, sarcoidosis and Sjogren's syndrome may coexist in the same patient and is now thought to share common pathologic process. This case is the first report of such coexistence in Korea.(Korean J Med 70:S352-S357, 2006) Key Words : Sjogren’s syndrome, Sarcoidosis, Colon

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