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Original Article
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Korean J Med. 2006;70(3):261-267.
- 원저 : 한국에서의 췌장의 낭성 종양 (Original Articles : The cystic neoplasms of the pancreas in Korea)
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윤원재, 윤용범, 이광혁, 이준규, 이우진, 류지곤, 이규택, 문영수, 이동기, 최호순, 김용태, 박
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Won Jae Yoon, Yong Bum Yoon, Kwang Hyuck Lee, Jun Kyu Lee, Woo Jin Lee, Ji Kon Ryu, Kyu Taek Lee, Young Soo Moon, Dong Ki Lee, Ho Soon Choi, Yong Tae Kim,
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Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea
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- Abstract
- Background : Cystic neoplasms of the pancreas are being recognized with increased frequency.
In 1993, a report on 123 cases of cystic neoplasms of the pancreas diagnosed over a period of 32
years was published in Korea. Many changes on the concept of cystic neoplasms of the pancreas
have been made, including classification and diagnostic criteria. The present study was conducted
wherein a new survey on cystic neoplasms of the pancreas in Korea.
Methods
: Cystic neoplasms of the pancreas diagnosed over a period of 12 years, from 1993 to
2004 in 25 university hospitals throughout Korea were collected. They were classified according to
the World Health Organization classification of cystic neoplasms of the pancreas.
Results
: A total of 1264 cases of cystic neoplasms of the pancreas were diagnosed. The
diagnoses and frequencies are as follows: intraductal papillary mucinous neoplasm, 499 (39.5%);
mucinous cystic neoplasm, 318 (25.2%); serous cystic neoplasm, 232 (18.4%); solid pseudopapillary
neoplasm, 192 (15.2%); cystic endocrine neoplasm, 11 (0.8%); lymphoepithelial cyst, 8 (0.6%); acinar
cell neoplasm, 3 (0.2%); mature teratoma, 1 (0.1%). Increase in the annual number of diagnoses was
evident. In intraductal papillary mucinous neoplasm and mucinous cystic neoplasm, a significant
increase in mean age was seen in patients with malignant neoplasms.
Conclusions
: Cystic neoplasms of the pancreas are diagnosed with increasing frequency in Korea,
the most common being intraductal papillary mucinous neoplasm of the pancreas. In intraductal
papillary mucinous neoplasm and mucinous cystic neoplasm, the grade of dysplasia increased with
mean age, suggesting an adenoma-carcinoma sequence.(Korean J Med 70:261-267, 2006)
Key Words : Pancreas, Neoplasm, Cyst
Keywords :Pancreas, Neoplasm, Cyst
