The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2005;69(3):988-993.
증례 : 인간면역부전 바이러스 초감염 3예 : 조기 인지의 임상적 중요성
정성주&#;정은석&#;김정엽&#;정혜원&#;박대원&#;손장욱&#;김민자, , , , , ,
Three cases of primary human immunodeficiency virus infection and clinical implication of its early recognition
Sung Joo Jung, Eun Sun Jung, Jeong-Yup Kim, Hye Won Jeong, Dae Won Park, Jang-Wook Sohn, Min Ja Kim
Department of Medicine, Sungkyunkwan University School of Medicine


Abstract
Primary HIV infection (PHI) is the period from initial infection with HIV to complete seroconversion and can presented in a variety of ways. Persons with symptomatic PHI are highly contagious and play a key role in HIV spread. More than 90% of acute infection go undiagnosed despite more than 50% of cases are symptomatic. As the newly diagnosed HIV infected patients have increased in South Korea recent years, persons with PHI should be included in the targeted public health strategies. We recently experienced three cases of symptomatic PHI; the first case presented with whole body rash and general weakness, the second presented as mononucleosis-like syndrome and aseptic meningitis, and the last showed as only fever and myalgia. We suggest that general practitioners realize the clinical impact of PHI on the spread of HIV and importance of its early detection.(Korean J Med 69:S988-S993, 2005)

Keywords :Acute HIV Infection, Manifestations
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