Korean J Med > Volume 101(5); 2026 > Article
Endocrinology-metabolism
The Korean Journal of Medicine 2026;101(5):267-271.
Published online October 1, 2026.
DOI: https://doi.org/10.3904/kjm.2026.101.5.267   
Rapid Progression to End-Stage Kidney Disease and Anuria Following Finerenone Initiation in a Patient with Advanced Diabetic Kidney Disease
Jung Soon Kim1, Hong Il Lim2, So Young Lee1, Hyo-Jeong Kim3, Kyong Yeun Jung3, Jin Taek Kim3
1Division of Nephrology, Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
2Division of Nephrology, Department of Internal Medicine, Dongguk University Gyeongju Hospital, Dongguk University School of Medicine, Gyeongju, Korea
3Division of Endocrinology and Metabolism, Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
피네레논 초기 투여 후 급격한 신기능 악화 증례
김정순1, 임홍일2, 이소영1, 김효정3, 정경연3, 김진택3
1을지대학교 의과대학 노원을지대학교병원 신장내과
2동국대학교 의과대학 동국대학교경주병원 신장내과
3을지대학교 의과대학 노원을지대학교병원 내분비내과
Correspondence: 
Jung Soon Kim, Tel: +82-2-970-8619, Fax: +82-2-970-8457, Email: jtkimmd@eulji.ac.kr
Received: 8 September 2025   • Revised: 16 December 2025   • Accepted: 26 December 2025
Abstract
This case report describes a 70-year-old woman with advanced diabetic kidney disease who developed end-stage kidney disease (ESKD) and complete anuria within seven weeks of initiating finerenone therapy. This case highlights the need for caution when prescribing finerenone to patients with severely impaired renal function, particularly those with minimal residual renal reserve. Clinicians should be vigilant for signs of renal decompensation during the early phases of therapy.
Key Words: Diabetic nephropathies; Renal insufficiency; Mineralocorticoid receptor antagonists; Renal dialysis
주제어: 당뇨병성 신증; 신부전; 무기질코르티코이드 수용체길항제; 신대체 요법


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