Korean J Med > Volume 101(4); 2026 > Article
Nephrology
The Korean Journal of Medicine 2026;101(4):209-214.
Published online August 1, 2026.
DOI: https://doi.org/10.3904/kjm.2026.101.4.209   
Hamman Syndrome as a Rare Complication of Diabetic Ketoacidosis in a Patient with Chronic Heavy Alcohol Use: A Case Report
Yujin Shin1, Sang Won Lee1, Soo Jin Lee1, Kyung Pyo Kang1,2
1Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea
2Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Korea
과도한 음주력이 있는 당뇨병성 케토산증 환자에서 발생한 하만증후군 1예
신유진1, 이상원1, 이수진1, 강경표1,2
1전북대학교 의과대학 내과학교실
2전북대학교병원 의생명연구원
Correspondence: 
Kyung Pyo Kang, Tel: +82-63-250-2361, Fax: +82-63-254-1609, Email: kpkang@jbnu.ac.kr
Received: 14 October 2025   • Revised: 7 November 2025   • Accepted: 19 November 2025
Abstract
A 40-year-old man with altered mental status, abdominal pain, and vomiting was referred to our emergency department. Chest radiography revealed pneumomediastinum, raising concern for Boerhaave syndrome. Laboratory tests revealed high-anion-gap metabolic acidosis and hyperglycemic ketoacidosis, consistent with diabetic ketoacidosis (DKA). Endoscopic evaluation excluded esophageal perforation. Because the pneumomediastinum resolved with conservative management and DKA treatment, Hamman syndrome was diagnosed. The patient developed multiorgan dysfunction and required intensive care management, including mechanical ventilation and continuous renal replacement therapy. This case illustrates the diagnostic challenges of differentiating DKA from alcoholic ketoacidosis and Hamman syndrome from Boerhaave syndrome, highlighting the importance of a systematic approach and multidisciplinary critical care management for patients with severe metabolic derangements and multiorgan dysfunction.
Key Words: Diabetic ketoacidosis; Hamman syndrome; Mediastinal emphysema; Acute kidney injury
주제어: 당뇨병성 케톤산증; 하만증후군; 자발성 종격동 기종; 급성 신손상


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