Korean J Med > Volume 100(3); 2025 > Article
Gastroenterology
The Korean Journal of Medicine 2025;100(3):128-136.
Published online June 1, 2025.
DOI: https://doi.org/10.3904/kjm.2025.100.3.128   
A Case of IgG4-Related Disease of Gastrointestinal Origin Suspected to be Lymphoma and Actinomyces Infection
Young Cheon Ra, Eun Sun Kim, Hoon Jai Chun, Yoon Tae Jeen, Bora Keum, Hyuk Soon Choi, Han Jo Jeon, Sang Hyun Kim, Bomee Lee
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
림프종과 방선균증으로 의심되던 위장관 발생 IgG4 연관 질환 1례
라영천, 김은선, 전훈재, 진윤태, 금보라, 최혁순, 전한조, 김상현, 이보미
고려대학교 의과대학 고려대학교 안암병원 소화기내과
Correspondence: 
Eun Sun Kim, Tel: +82-2-920-6553, Fax: +82-2-920-6553, Email: silverkes@naver.com
Received: 18 May 2025   • Revised: 11 September 2024   • Accepted: 15 November 2024
Abstract
Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by the tendency to form tumefactive lesions. However, the disease has highly variable clinical manifestations, as IgG4-RD can affect any organ. The biliary tree and major salivary glands are commonly affected; however, bowel mucosa is rarely affected. A 41-year-old man presented to our hospital complaining of abdominal pain. Computed tomography and endoscopy were performed at another hospital, and a biopsy was performed on a lesion suspected to be malignant. Biopsy revealed no remarkable findings other than lymphoid hyperplasia. Subsequently, IgG4-RD was confirmed via surgical biopsy. The disease and its symptoms were successfully treated with steroid therapy.
Key Words: Immunoglobulin G4-related disease; Autoimmune diseases; Gastrointestinal tract; Case reports
주제어: IgG4 연관 질환; 자가면역질환; 소화기계 질환; 증례 보고


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