Korean J Med > Volume 88(6); 2015 > Article
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The Korean Journal of Medicine 2015;88(6):711-714.
Published online June 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.6.711   
A Case of Tubulointerstitial Nephritis and Uveitis with Fanconi Syndrome
Miyeon Kim1, Hyun Woo Kim1, Ji Young Kim1, Jinho Jeong2, Eun-Jung Park1, Jinseok Kim1, So Mi Kim1
1Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea
2Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea
판코니 증후군을 동반한 간질성 신염 포도막염 증후군 1예
김미연1, 김현우1, 김지영1, 정진호2, 박은정1, 김진석1, 김소미1
1제주대학교 의학전문대학원 제주대학교병원 내과
2제주대학교 의학전문대학원 제주대학교병원 안과
Correspondence: 
So Mi Kim, Tel: +82-64-717-1400, Fax: +82-64-717-1402,, Email: zhidao79@naver.com
Received: 9 August 2014   • Revised: 30 September 2014   • Accepted: 15 October 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease that comprises 4.7% of acute interstitial nephritis. With reno-ocular manifestations, TINU syndrome is accompanied by symptoms such as fever, fatigue, malaise, anorexia, vomiting, and arthralgia. TINU syndrome is reported mainly in children or adolescent girls, and it is rare in adults. Although TINU syndrome can present with multiple renal tubular defects, Fanconi syndrome characterized by generalized impairment of proximal tubular function, leading to renal glucosuria, hyperuricosuria, hyperphosphaturia, proximal renal tubular acidosis, and kaliuresis leading to hypokalemia, has rarely been described. We report a case of TINU syndrome with Fanconi syndrome in a 46-year-old HLA B27-positive Korean woman.
Key Words: Nephritis, Interstitial; Uveitis; Fanconi syndrome
주제어: 간질성 신염; 포도막염; 판코니증후군


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