Korean J Med > Volume 88(5); 2015 > Article
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The Korean Journal of Medicine 2015;88(5):593-597.
Published online May 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.5.593   
Unusual CAPD Citrobacter freundii Peritonitis Complicated by a Fungal Infection, Identified by 16s Ribosomal RNA Gene Sequencing
Tae Ryom Oh, Seong Kwon Ma, Soo Wan Kim
Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
16s ribosomal RNA의 염기서열 분석으로 진단된 진균 감염이 합병된 Citrobacter freundii 복막투석 복막염 1예
오태렴, 마성권, 김수완
전남대학교 의과대학 내과학교실
Correspondence: 
Soo Wan Kim, Tel: +82-62-220-6271, Fax: +82-62-225-8578, Email: skimw@chonnam.ac.kr
Received: 31 July 2014   • Revised: 20 August 2014   • Accepted: 3 September 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We present a case of continuous ambulatory peritoneal dialysis peritonitis caused by Citrobacter freundii complicated by a fungal infection with abscess formation. A 34-year-old woman was admitted to our hospital with abdominal pain. Isolate cultures were confirmed as Citrobacter freundii by DNA sequencing of the 16s ribosomal ribonucleic acid (RNA). Antibiotic therapy was ineffective and Candida tropicalis was isolated in follow-up blood cultures. We administered an antifungal agent and removed the peritoneal catheter. A sudden fever developed, and abdominal computed tomography showed intra-abdominal abscesses. Percutaneous drainage was performed, but no bacteria were cultured. After draining the abscesses, the patient recovered. Citrobacter species are unusual pathogens in peritonitis, and fungal peritonitis is a serious complication of bacterial peritonitis. Indwelling catheters should be removed and appropriate antibiotic therapy provided. Suspicion of a fungal infection combined with bacterial peritonitis will improve the prognosis of patients on peritoneal dialysis.
Key Words: Continuous ambulatory peritoneal dialysis; Citrobacter; Peritonitis
주제어: 지속적 외래 복막투석; Citrobacter; 복막염


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