| Spontaneous Arterial Bleeding in Patients with Alcoholic Liver Cirrhosis: a Series of Three Cases |
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Choon Sik Seon1, Yunju Jo1, Jihyun Lee1, Young Kwan Jo1, Sang Bong Ahn1, Byungkwan Son1, Young Kwon Jo2 |
1Departments of Internal Medicine, Eulji University School of Medicine, Seoul, Korea
2Departments of Radiology, Eulji University School of Medicine, Seoul, Korea |
| 알코올 간경변 환자에서 발생한 자발성 동맥 출혈의 3예 |
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선춘식1, 조윤주1, 이지현1, 조영관1, 안상봉1, 손병관1, 조영권2 |
1을지대학교 의과대학 내과학교실
2을지대학교 의과대학 영상의학과교실 |
Correspondence:
Yunju Jo, Tel: +82-2-970-8624, Fax: +82-2-970-8621, Email: jyj1138@eulji.ac.kr
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Received: 27 February 2014 • Revised: 1 April 2014 • Accepted: 9 May 2014 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| Abstract |
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Spontaneous arterial bleeding has been reported rarely. In a patient consuming heavy amounts of alcohol with alcoholic liver cirrhosis, spontaneous bleeding can be evoked by thrombocytopenia, altered platelet function, and shear stress on fully dilated arteries by portal hypertension. Alcohol consumption itself can also predispose a patient to bleeding by influencing the aggregation and activation of platelets, and altering the coagulation and fibrinolysis pathway. All of these mechanisms could cause patients with alcoholic liver cirrhosis to bleed spontaneously; however, conditions inducing peripheral arterial bleeding are very rare. Here, we report three cases of spontaneous arterial bleeding in patients with liver cirrhosis consuming heavy amounts of alcohol. All of the patients bled without any physical trauma, and the involved arteries were the intercostal arteries in two cases and a gastroduodenal artery in the other case. The patients were treated by angiographic embolization. One expired due to recurrence of arterial bleeding despite repeated angiographic embolization and massive transfusion. |
| Key Words:
Hemorrhage; Liver cirrhosis, alcoholic; Embolization, therapeutic |
| 주제어:
출혈; 알코올간경변; 치료 색전술 |
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