Korean J Med > Volume 86(5); 2014 > Article
The Korean Journal of Medicine 2014;86(5):651-654.
Published online May 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.5.651   
Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient
Hye Yun Jeong, San Ha Kang, Ji Hyun Song, Sun Young Shin, Daniel Min, Kyu Hyun Han, Jin Jung Choi
Division of Rheumatology, Department of Internal Medicine, Bundang CHA Medical Center, CHA University, Seongnam, Korea
전신홍반루푸스의 비장경색으로 처음 발현된 항인지질 증후군 1예
정혜윤, 강산하, 송지현, 신선영, 민다니엘, 한규현, 최진정
차의과학대학교 분당차병원 내과
Correspondence: 
Jin Jung Choi, Tel: +82-31-780-5224, Fax: +82-31-780-5208, Email: jinjungchoi@cha.ac.kr
Received: 25 June 2013   • Revised: 6 August 2013   • Accepted: 16 October 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient. (Korean J Med 2014;86:651-654)
Key Words: Lupus erythematosus; Systemic; Antiphospholipid syndrome; Splenic infarction
주제어: 전신홍반루푸스; 항인지질 증후군; 비장경색


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