| A Case of Hyperkalemic Periodic Paralysis Induced by Diabetic Nephropathy |
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Chang Seog Lee1, Jung Min Park1, Min Seong Kim1, Ju Ho Lee2, Do Young Kim1, Young Bae Lim1, Yong Kyu Lee1 |
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| 당뇨병신증에서 발생한 고칼륨혈증 주기마비 1예 |
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이창석1, 박정민1, 김민성1, 이주호2, 김도영1, 임영배1, 이용규1 |
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| Abstract |
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Hyperkalemic periodic paralysis is characterized by episodic flaccid paralysis of the skeletal muscles due to an increase in serum potassium concentrations. Primary hyperkalemic periodic paralysis is caused by point mutations in SCN4A, encoding a voltage-gated skeletal muscle sodium channel. However, hyperkalemia-related diseases, such as renal failure, adrenal insufficiency, hypoaldosteronism, and chronic diuretic use, can induce secondary hyperkalemic periodic paralysis. Diagnosis of this disease is based on clinical features, nerve conduction studies, and a DNA sequence analysis. In cases of diagnostic uncertainty, a provocation test can be used to ensure the correct diagnosis. Here, we report a case of secondary hyperkalemic periodic paralysis with hyperkalemia that was induced by diabetic nephropathy, and review the relevant literature. |
| Key Words:
Diabetic Nephropathy; Hyperkalemic Periodic; Paralysis |
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