Korean J Med > Volume 77(5); 2009 > Article
The Korean Journal of Medicine 2009;77(5):1289-1292.
Wernicke-Korsakoff encephalopathy following cancer treatment in a patient with schizophrenia
Ji Chan Park, Suk Young Park, Dae Won Kim, Seok Hwan Kim, Eun Hye Kim, Sung Jin Lee, Su Sun Chang
정신분열병 환자에서 암치료 후 발생한 베르니케 코르사코프 뇌병증 1예
박지찬·박석영·김대원·김석환·김은혜·이성진·장수선, Suk Young Park, Dae Won Kim, Seok Hwan Kim, Eun Hye Kim, Sung Jin Lee, Su Sun Chang
Abstract
We present a case of Wernicke-Korsak off encephalopathy due to prolonged vomiting and unbalanced nutrition in a patient with schizophrenia and esophageal and gastric cancer. The patient’s psychiatric illness and cancer treatment led to either psychiatric deterioration or brain metastasis, which delayed thiamine treatment. Owing to its high mortality and morbidity, Wernicke encephalopathy should be considered in any patient with confusion, gait disturbance, and nystagmus, especially if associated with malnutrition. This is particularly important in a patient with psychiatric illness or cancer in which the clinical history and symptoms may be similar and treatment may be delayed. (Korean J Med 77:S1289-S1292, 2009)
Key Words: Cancer; Schizophrenia; Wernicke-Korsakoff encephalopathy


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