| A case of metronidazole induced encephalopathy in a cirrhotic patient |
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Sang Hee Kim, Jin Il Kim, Yong Jai Park, So Young Lee, Seung Chul Yu, Hyeon Seong Kim, Yu Ri Shin |
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| 간경변증 환자에서 메트로니다졸 유발 뇌증 |
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김상희, 김진일, 박용재, 이소영, 유승철, 김현성, 신유리 |
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| Abstract |
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Metronidazole induced encephalopathy is a rare disease caused by the antibiotic drug, metronidazole. Metronidazole is a nitroimidazole antibiotic used for anaerobic infections, Helicobacter pylori infection and spontaneous bacterial peritonitis.
Metronidazole has good cellular penetration and is believed to penetrate the CSF and central nervous system. The incidence of metronidazole induced encephalopathy is unknown, though several previous studies have addressed brain changes caused by metronidazole neurotoxicity. Neurologic side effects include peripheral neuropathy, seizures, encephalopathy, dysarthria, and ataxia. We experienced a case of metronidazole induced encephalopathy, diagnosed by brain MRI in a patient with spontaneous bacterial peritonitis and performed follow-up imaging after discontinuation of metronidazole. |
| Key Words:
Metronidazole; Encephalitis |
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