A case of pneumomediastinum combined with chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation |
Ho Sup Lee, Seong Hoon Shin, Yang Soo Kim |
포항성모병원 1내과, 2비뇨기과 |
조혈모세포이식 후에 만성 이식편대 숙주반응과 동반된 종격동 기종 1예 |
이호섭, 신성훈, 김양수 |
Departments of 1Internal Medicine and 2Urology, Pohang Saint Mary’s Hospital, Pohang, Korea |
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Abstract |
Pulmonary complications are very common after allogeneic stem cell transplantation and are sometimes serious. Late-onset noninfectious pulmonary complications of chronic graft-versus-host disease (GVHD) after allogeneic stem cell transplantation include bronchiolitis obliterans and bronchiolitis obliterans with organizing pneumonia. Especially, bronchiolitis obliterans is correlated with GVHD. If they occur simultaneously, serious pulmonary and subcutaneous complications such as pneumomediastinum, subcutaneous emphysema, and pneumothorax can occur. We present the case of a 19-year-old man who had pneumomediastinum, subcutaneous emphysema, and pneumothorax with GVHD after allogeneic stem cell transplantation. |
Key Words:
Pneumomediastinum; Allogeneic stem cell transplantation; Graft-versus-host disease; Bronchiolitis obliterans |
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