| Primary systemic anaplastic large-cell lymphoma presenting as ascites |
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Jin Myung Park, Seung Joo Kang, Mi Na Kim, Su Hyun Kim, Hyun Jin Jo, Mun Sun Choi, Ji Won Kim |
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| 복수로 발현한 원발성 전신형 비정형 거대세포 림프종 1예 |
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박진명, 강승주, 김미나, 김수현, 조현진, 최문선, 김지원 |
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| Abstract |
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Here, we report an unusual case of anaplastic large-cell lymphoma presenting as ascites. A 62-year-old man with alcoholic liver
cirrhosis was admitted for ascites. The ascites was an exudate, and atypical cells with nuclear irregularity suggesting the presence of
a lymphoma were found on cytological examination of the ascites. However, no primary lesion was found after an exhaustive physical,
laboratory, endoscopic, and radiologic examination, and the atypical cells were negative for human herpes virus-8 DNA.
Therefore, no definitive diagnosis was made. He was followed regularly without chemotherapy. After 30 months, iliopsoas and
erector spinae muscle lesions developed. An ultrasonography-guided gun biopsy of the iliopsoas muscle lesion was performed that
revealed anaplastic pleomorphic tumor cells. An immunohistochemical study showed that the tumor cells were positive for LCA
and CD30 and negative for CK and ALK. The patient was diagnosed with a primary systemic anaplastic large-cell lymphoma. He
could not undergo chemotherapy due to acute renal failure and died after 10 days. (Korean J Med 76:S181-S185, 2009) |
| Key Words:
Antigens; CD30; Lymphoma; Large cell; Anaplastic; Ascites |
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