Korean J Med > Volume 75(3); 2008 > Article
The Korean Journal of Medicine 2008;75(3):811-814.
Diffuse large B-cell lymphoma in a patient with neurofibromatosis type I
Chun Young Song, Young Hwa Ki, Yun Mi Song, Gun Min Kim, Ji Chan Park, Yeon Soo Kim, Jong Ok Kim
증례 : 제1형 신경섬유종증 환자에서 발생한 미만 대 B 세포 림프종 1예
송춘영.기영화.송윤미.김건민.박지찬.김연수.김종옥, Young Hwa Ki, Yun Mi Song, Gun Min Kim, Ji Chan Park, Yeon Soo Kim, Jong Ok Kim
Abstract
Neurofibromatosis or von Recklinghausen’s disease is a common autosomal dominant disorder that has an increased risk of developing cancer and is an important cause of morbidity and mortality. Malignant tumors of the nervous system often coexist with neurofibromatosis, and are associated with NF1 gene mutations. There are no differences in the treatment and prognosis of neurofibromatosis patients. Malignant lymphoma rarely coexists with neurofibromatosis type 1 and consists mostly of T cell lymphoma. We experienced a rare case of diffuse large B-cell lymphoma in a patient with neurofibromatosis type 1. (Korean J Med 75:S811-S814, 2008)
Key Words: Neurofibromatosis 1; Lymphoma; Large-cell; Diffuse


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