Korean J Med > Volume 75(3); 2008 > Article
The Korean Journal of Medicine 2008;75(3):720-725.
Liver transplantation for metastatic colon cancer with hepatic failure: A case report
Seung Woo Yi, Jun Yong Park, Semi Park, Jun Chul Park, Jae Jun Park, Nae Chun Yoo, Chae Yoon Chon
증례 : 대장암의 간전이 및 간부전으로 인한 간이식 1예
이승우.박준용.박세미.박준철.박재준.유내춘.전재윤, Jun Yong Park, Semi Park, Jun Chul Park, Jae Jun Park, Nae Chun Yoo, Chae Yoon Chon
Abstract
The liver is the most common site of distant metastasis of colorectal cancer, and surgical resection is the only therapy that offers the possibility of a cure. However, only 10~20% patients with colorectal liver metastases are candidates for surgical resection upon initial presentation. For patients with unresectable liver metastasis, systemic chemotherapy or hepatic arterial chemoembolization, radiofrequency thermal ablation and immunotherapy are used as alternative therapies. In general, colorectal liver metastasis is an absolute contraindication for liver transplantation. Here, we present the case of a patient who has survived cancer-free for more than 2 years after liver transplantation as rescue therapy for acute hepatic failure after chemoembolization for liver metastasis from colon cancer. This case demonstrates that liver transplantation may be a curative modality in selected patients with hepatic failure and colorectal liver metastasis. (Korean J Med 75:S720-S725, 2008)
Key Words: Colon cancer; Hepatic failure; Liver metastasis; Liver transplantation


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