Korean J Med > Volume 75(1); 2008 > Article
The Korean Journal of Medicine 2008;75(1):77-81.
A case of typhoid fever with manifestations of acute hepatitis
Jong Woon Hwang, Ho Myung Lee, Dae Hee Han, Ji Eun Oh, Jung Su Ha, Dae Hyeon Cho, Sang Goon Shim
경희대학교 의과대학 순환기내과학교실
증례 : 급성 간염으로 발현된 장티푸스 1예
황종운.이호명.한대희.오지은.하정수.조대현.심상군, Ho Myung Lee, Dae Hee Han, Ji Eun Oh, Jung Su Ha, Dae Hyeon Cho, Sang Goon Shim
Abstract
Typhoid fever is a febrile illness with a variety of systemic manifestations; however, icteric typhoid hepatitis, mimicking the clinical features of acute hepatitis, is very uncommon. A 45-year-old man was admitted to the hospital for evaluation of fever, dark-colored urine, and jaundice. On admission, the total bilirubin was 4.3 mg/dL, and the AST and ALT were 468 and 319 IU/L, respectively. Salmonella typhi was identified by blood culture. A liver biopsy revealed some mononuclear cell infiltrations without hepatocyte necrosis or typhoid nodules. CT scan findings showed splenomegaly and mesenteric lymphadenopathy. With the administration of ceftriaxone, he became afebrile and showed improvement in the jaundice, with normalization of AST and ALT. (Korean J Med 75:77-81, 2008)
Key Words: Typhoid fever; Salmonella typhi; Hepatitis


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