| Two cases of infliximab treatment in Patients with Behcet’s disease and intractable colon ulcers |
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Jun Cheol Yoon, Jun Hyuk Seo, Do Hwae Park, Sun Taek Choi, Young Ho Sung, Chan Woo Lee, Dong Ho Oh |
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경희대학교 의과대학 순환기내과학교실 |
| 증례 : 난치성 대장궤양을 동반한 베체트병 환자에서 infliximab 치료 2예 |
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윤준철 . 서준혁 . 박도회 . 최선택 . 성영호 . 이찬우 . 오동호, Jun Hyuk Seo, Do Hwae Park, Sun Taek Choi, Young Ho Sung, Chan Woo Lee, Dong Ho Oh |
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| Abstract |
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Behcet’s disease is a chronic disease characterized by recurrent systemic vasculitis. The pathogenesis remains unclear. This disease involves various organs of the body and it can have a variety of symptoms with an unpredictable course. The diagnosis of Behcet’s disease is made in patients with oral and genital ulcers and uveitis. In addition, gastrointestinal symptoms are frequently present; however, intestinal ulcers are infrequent. The most common extra-oral sites of gastrointestinal involvement are ileocecal and colon lesions. The lesions are typically resistant to medical treatment and frequently recur after surgical treatment. Here we present two cases treated with the monoclonal antibody anti-tumor necrosis factor (TNF) and regression of all symptoms. |
| Key Words:
Behcet’s disease, Ulceration of intestine, Anti-TNF α treatment |
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