| A case of gastric hepatoid adenocarcinoma misdiagnosed as an extragonadal germ cell tumor |
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Seong-Hoon Jeong, Hyun-Jeong Shim, Jun-Eul Hwang, Sang-Ho Kim, Seong-Rye Seo, Seong-Uk Lim, Ik-Joo Chung |
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이화여자대학교 의과대학 내과학교실 |
| 증례 : 생식 세포종양으로 오인된 위의 간세포양 샘암종 1예 |
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정성훈, 심현정, 황준일, 김상호, 서성례, 임성욱, 정익주 |
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Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea |
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| Abstract |
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Hepatoid adenocarcinoma is a rare variant of adenocarcinoma that can occur in the stomach. This neoplasm has a poor
prognosis and it frequently presents at an advanced stage of disease; it is clinically characterized by increased serum
levels of alpha-fetoprotein (AFP) in most cases.
We experienced a case of hepatoid adenocarcinoma of the stomach with multiple liver metastases that mimicked germ
cell tumor in a 43-year-old man. He had incidentally detected gastric adenocarcinoma via gastrofibroscopy and he
underwent subtotal gastrectomy. The postoperative pathologic stage was II (T2N1M0). He complained of epigastric pain.
The serum AFP was markedly increased (227,325 IU/mL) and abdominal CT revealed multiple liver masses. We
considered these as extragonadal germ cell tumors that occurred in the liver because of the markedly elevated AFP, the
short duration of follow-up and early stage of stomach cancer at the that time. To confirm the diagnosis, biopsy of liver
mass was done and he was diagnosed with hepatoid adenocarcinoma.(Korean J Med 73:107-111, 2007)
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| Key Words:
Gastric cancer, Alpha-fetoproteins |
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