| The meaning of warning symptoms in the patients with dyspepsia |
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Chang Hee Han, Joon Seong Lee, Jae Ouk Ahn, Sang Hoon Jun, In Seop Jung, Bong Min Koh, Su Jin Hong, Chang Bum Ryu, Jin Oh Kim, Joo Young Cho, Moon Sung Lee, Chan Sup Shim, Boo Sun |
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중앙대학교 의과대학 내과학교실 |
| 원저 : 소화불량증 환자에서 경고증상의 의미에 대한 연구 |
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한창희, 이준성, 안재억, 전상훈, 정인섭, 고봉민, 홍수진, 유창범, 김진오, 조주영, 이문성, 심찬섭, 김부성 |
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Department of Internal Medicine, College of Medicine, Chungang University, Seoul, Korea |
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| Abstract |
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Background : We tried to assess whether the presence of warning symptoms and age could be useful indicators for
performing endoscopy in patients who suffer from various organic gastrointestinal diseases.
Methods : Between May 2005 to August 2005, 827 subjects who visited the health care center were studied via
questionnaires and performing upper endoscopy. The questionnaires evaluated the presence and pattern of dyspepsia and
the warning symptoms.
Results : A total of 808 patients were enrolled. The mean age of patients was 44.6±8.9 years (mean±SD) with a
male to female ratio of 1.2:1. 153 patients (18.9%) were diagnosed with confirmed organic diseases and 52 patients (6.4%)
were diagnosed with definite organic diseases. The total number of organic diseases and definite organic diseases
(gastroduodenal ulcer, reflux esophagitis and advanced gastric cancer) was statistically higher in the male population
(p=0.001 in both). The relative risk of dyspepsia, the presence of warning symptoms and each warning symptom for the
organic disease and definite organic diseases were not consistently higher for the males or females. The males over fifty
years and the males over sixty years age had a relative risk of 2.046 (95% CI: 1.27～3.30) and 3.105 (95% CI: 1.39～6.95)
for organic disease and 1.913 (95% CI: 0.97～3.77) and 5.333 (95% CI: 2.15～13.22) for definite organic disease,
respectively. For the male patients over fifty or sixty years old with dyspepsia or warning symptoms, there were
tendencies to increase the relative risk of definite organic disease rather than organic disease.
Conclusions : The relative risk of organic diseases in the presence of warning symptoms in males of over fifty years
or sixty years age was not sufficiently significant for differentiating organic diseases. Thus, warning symptoms, old age
and presence of dyspepsia alone can not be used as a predictor to guide endoscopic examination.(Korean J Med 73:25-33,
2007)
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| Key Words:
Dyspepsia, Warning symptom, Gastrointestinal diseases |
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