| A case of Non-Hodgkin’s lymphoma following Hodgkin’s lymphoma |
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이화여자대학교 의과대학 내과학교실 |
| 증례 : 호지킨 림프종 완치 후 발생한 비호지킨 림프종 1예 |
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김세희&#;최주현&#;김 신&#;한은미&#;허주령&#;강윤구&#;서철원, , , , , , |
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Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea |
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| Abstract |
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It is rare that two different histologic types of lymphoma develop in the same person. Composite lymphoma is defined as 2 distinctly demarcated types of non-Hodgkin's lymphoma (NHL) or its rare association with Hodgkin's lymphoma (HL) within a single organ or tissue. Discordant lymphoma is defined as 2 types of NHL or the rare association of HL with NHL at different anatomic sites in the same patient. Sequential lymphoma is defined as 2 different types of lymphoma occurring in the same person sequentially. A 48 year-old woman had been diagnosed with HL at the left neck 26 months ago and she was treated with chemotherapy and local radiotherapy; she then re- visited our hospital with a recurred neck mass. An excisional biopsy was performed and the pathologic diagnosis was NHL of the diffuse large B-cell type. She underwent 3 rounds of chemotherapy (Rituximab+ESHAP) and also autologous stem cell transplantation. Until now, she has not had any evidence of lymphoma recurrence. This might be the first sequential lymphoma case in Korea. However, the possibility of a secondary malignancy cannot be excluded.(Korean J Med 71:S1105-S1111, 2006) |
| Key Words:
Sequential lymphoma, Composite lymphoma |
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