| A case of successful treatment of central nervous system (CNS) aspergillosis after hematopoietic stem cell transplantation with voriconazole |
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연세대학교 의과대학 내과학교실, 심장혈관병원 심장내과, 심혈관 연구소 |
| 증례 : 조혈모세포이식술 후 보리코나졸로 치료한 중추신경계 아스페르길루스증 1예 |
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정종원, &#;양덕환, &#;김상호, &#;이세련, &#;김여경, &#;이제중, &#;김형준 |
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Department of Internal Medicine, Yonsei University College of Medicine. Cardiology division, Cardiovascular center, Cardiovascular research institute, Seoul, Korea |
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| Abstract |
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A 26-year-old man with relapsed chronic myelogenous leukemia following bone marrow transplantation received non-myeloablative stem cell transplantation (NST). After the NST, he complained of neurological deficit, with sustained fever. The brain MRI showed multiple ring-enhanced lesions in the cerebellum, pons and left periventricle. He was diagnosed with CNS aspergillosis from a stereotactic biopsy. Following treatment with voriconazole for 21 days, his follow up brain MRI showed a much regressed lesion, with considerably improved clinical symptoms. We reported a case of cerebral aspergillosis, which was successfully treated with voriconazole following NST.(Korean J Med 71:S1095-S1100, 2006) |
| Key Words:
Central nervous system aspergillosis, Voriconazole, Non-myeloablative stem cell transplantation (NST) |
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