| A case of progressive IgA nephropathy with pulmonary hemorrhage |
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이화여자대학교 의과대학 내과학교실 |
| 증례 : 폐출혈을 동반한 진행성 IgA 신병증 1예 |
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이용하&#;이민우&#;박무용&#;최수정&#;김진국&#;황승덕&#;권계원, , , , , , |
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Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea |
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| Abstract |
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Pulmonary renal syndrome is defined as a combination of diffuse pulmonary hemorrhage and glomerulonephritis. This condition includes Wegener's granulomatosis, Churg-Strauss vasculitis, systemic lupus erythematosus and IgA nephropathy. Although IgA nephropathy is the most common glomerulonephritis, extrarenal manifestations, including pulmonary hemorrhage, are rare complications. Pulmonary renal syndrome requires intensive treatment with corticosteroid and immunosuppressive agents. We report here on a case of Ig A nephropathy with pulmonary hemorrhage. A 17-year-old man was admitted because of hemoptysis. Chest X-ray showed bilateral pulmonary infiltration in the lower lung fields. He had dyspnea and oliguria. He was treated via hemodialysis and intensive therapy with pulse methylprednisolone and cyclophosphamide. Renal biopsy showed IgA nephropathy (grade V). Although the respiratory manifestation was improved, renal failure progressed to end-stage renal disease that required maintenance hemodialysis.(Korean J Med 71:1060-1065, 2006) |
| Key Words:
IgA nephropathy, Hemoptysis, End stage renal disease |
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