False positive uptake after high dose 131I ablation therapy in a pulmonary fungus ball and a mature ovarian dermoid cyst in patients suffering with papillary thyroid cancer

Korean J Med > Volume 71(3); 2006 > Article

Original Article

The Korean Journal of Medicine 2006;71(3):1030-1034.

False positive uptake after high dose 131I ablation therapy in a pulmonary fungus ball and a mature ovarian dermoid cyst in patients suffering with papillary thyroid cancer

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이화여자대학교 의과대학 내과학교실

증례 : 유두상 갑상선암 환자의 고용량 동위원소치료 후 131I 전신스캔에서 위양성 소견을 보인 폐 진균종 및 난소 기형종

노은숙&#;권혁상&#;김현진&#;김지현&#;윤건호&#;차봉연&#;손호영, , , , , ,

Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea

Abstract

Whole body 131I scintigraphy plays an important role for managing well-differentiated thyroid cancer after total or near total thyroidectomy, along with the measurement of the serum thyroglobulin level. However, false positive uptake on 131I whole body scans can occur, although this is not common, without the presence of any residual thyroid tissue or metastatic lesions. The exact mechanism of iodide uptake in a non-malignant lesion is not clear, except for physiologic uptake in some tissues. We report here on two cases of false positive uptake after high dose radioiodine therapy in a pulmonary fungus ball and a mature ovarian dermoid cyst in two patients who were suffering with papillary thyroid cancer.(Korean J Med 71:S1030-S1034, 2006)

Key Words: Thyroid cancer, False positive, Radioiodine