| Histological comparison of endoscopic forceps biopsy with endoscopic mucosal resection in the gastric lesions |
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Jee Yeon Kim, See Won Lee, Lee Chun Park, Jung Kwang Shin, Nam Young Park, Won Moon, Kyu Jong Kim, Moo In Park, Seun Ja Park, Hee Kyung Chang |
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고려대학교 의과대학 내과학교실 |
| 원저:위 점막 병변의 겸자 생검과 점막절제술 후의 조직 진단의 비교 |
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김지연, See Won Lee, Lee Chun Park, Jung Kwang Shin, Nam Young Park, Won Moon, Kyu Jong Kim, Moo In Park, Seun Ja Park, Hee Kyung Chang |
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| Abstract |
Background : The correct histological diagnosis of a gastric adenoma is important, because an
adenoma has been reported to be a precancerous lesion and is associated with focal gastric
carcinoma. However, there is some discrepancy between the histology of a forceps biopsy and
that of the endoscopic mucosal resection. This study compared the histological findings of a
gastric mucosal lesion in the specimens of a forceps biopsy and an endoscopic mucosal
resection.
Methods
: 88 cases of gastric mucosal lesions, which had been removed by the endoscopic
mucosal resection, were reviewed retrospectively. All the patients had undergone a forceps
biopsy before the endoscopic mucosal resection. The histological findings of the specimens by
a forceps biopsy were compared with those by resection.
Results
: The histological findings were accordant at 52 of the 88 cases (59.1%). Among the
71 cases with adenoma or gastritis in the biopsied specimens, 13 cases (18.3%) were finally
diagnosed with gastric cancer in the resected specimens. Among all the gastritis and adenomas
determined by the forceps biopsy, the high-risk groups for adenocarcinomas were characterized
by the following endoscopic findings: red-colored and depressed lesions.
Conclusions
: Biopsy specimens may not be representative of the entire lesion. Therefore, an
endoscopic resection of a gastric mucosal lesion is needed for making an accurate histological
diagnosis and treatment if adenomas such as red-colored or depressed lesions are suspected.
(Korean J Med 71:600-608, 2006)
Key Words : Gastric mucosal disease, Forceps biopsy, Endoscopic mucosal resection, Histolgy |
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