Central catheter-related bloodstream infection caused by Mycobacterium mucogenicum in an acute myeloid leukemia patient |
Sung Hye Kim, Woo Jin Jeong, Sang Ho Choi, Mi Na Kim, Yang Soo Kim, Jun Hee Woo |
고려대학교 의과대학 내과학교실 |
증례:급성 골수성 백혈병환자에서 발생한 중심정맥관 관련 Mycobacterium mucogenicum 균혈증 1예 |
김성혜, Woo Jin Jeong, Sang Ho Choi, Mi Na Kim, Yang Soo Kim, Jun Hee Woo |
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Abstract |
Mycobacterium mucogenicum is the one of rapidly growing mycobacteria identified in 1995;
so far, only few cases have been reported that were associated with dialysis equipment or
central venous catheter. Here we present a central catheter-related M. mucogenicum
bloodstream infection in a 48-year-old woman with acute myeloid leukemia. She presented with
fever and was empirically treated with ceftazidime and piperacillin. Since the fever resolved
within 24 hours, she underwent bone marrow transplantation as scheduled. Four days before
stem cell infusion, M. mucogenicum grew from the blood cultures that were drawn through a
central venous catheter and from peripheral blood. The central venous catheter was removed
and the cultured organism was identified to be M. mucogenicum by sequence analysis of the
16S ribosomal RNA. She was further treated for 8 weeks with cefoxitin and amikacin as the
bacteria were confirmed to be susceptible by broth microdilution test. There has been no
episode of recurrence during the 6-month follow-up.(Korean J Med 71:582-586, 2006)
Key Words : Mycobacterium mucogenicum, Bacteremia, Acute leukemia |
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