A case of ectopic parathyroid carcinoma presenting with renal failure and anemia |
Myong Su Kang, Ho Yun Lee, Pyong Ju Seo, Hee Jin Kim, Sung Chul Yun, Phil Won Seo, Mi Seon Kwon |
고려대학교 의과대학 내과학교실 |
증례:신부전과 빈혈로 발현된 이소성 부갑상선암 1예 |
강명수, Ho Yun Lee, Pyong Ju Seo, Hee Jin Kim, Sung Chul Yun, Phil Won Seo, Mi Seon Kwon |
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Abstract |
Parathyroid carcinoma is an uncommon cause of PTH-related hypercalcemia with a reported
incidence of 0.4% to 5% of all cases of primary hyperparathyroidism. Even though the clinical
manifestations of hyperparathyroidism are more severe in patients with parathyroid carcinoma than
in those with parathyroid adenoma, it is difficult to differentiate carcinoma from adenoma
preoperatively. Parathyroid carcinomas are usually larger and firmer than parathyroid adenomas and
patients with parathyroid carcinoma have a higher incidence of renal dysfunction, bone disease and
gastrointestinal symptoms. Anemia is an uncommon clinical feature of parathyroid carcinoma. There
have been no prior cases of ectopic parathyroid carcinomas reported to date. In this article, we report
the case of a 26-year-old man who developed severe anemia and acute renal failure due to an ectopic
parathyroid tumor and was diagnosed with parathyroid carcinoma postoperatively. His serum calcium
levels returned to normal and the anemia resolved postoperatively.(Korean J Med 71:435-441, 2006)
Key Words : Parathyroid neoplasm, Anemia, Renal insufficiency |
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