| Clinical courses and risk factors for renal graft survival in renal retransplantation patients |
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Byung Ha Chung, Hee Sun Jung, Si Hyun Kim, Kwi Young Kang, You Jung Nahm, Jin Soo Kim, Won Chul Kim, Jin Young Kim, Sang Woo Han, Bum Soon Choi, Chul Woo Yang, Yong Soo Kim, Byung Kee Bang |
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고려대학교 의과대학 내과학교실, 소화기 연구소 |
| 원저 : 신장 재 이식 환자의 임상양상과 이식 신 생존율에 영향을 미치는 인자 분석 |
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정병하&#;정희선&#;김시현&#;강귀영&#;남유정&#;김진수.김원철&#;김진영&#;한상우&, Hee Sun Jung, Si Hyun Kim, Kwi Young Kang, You Jung Nahm, Jin Soo Kim, Won Chul Kim, Jin Young Kim, Sang Woo Han, Bum Soon Choi, Chul Woo Yang, Yong Soo Kim, Byung Kee Bang |
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| Abstract |
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Background : It has been reported that the results of second renal transplantation are inferior to that of first transplantation and affected by several factors. The purpose of this study is to suggest guidelines for successful retransplantion by evaluating the factors which might affect the clinical courses and graft survival rates in the second renal transplantation.
Methods : Between March 1969 and February 2005, 1476 kidneys were transplanted in Kangnam St Mary’s hospital. Among these, 77 cases were retransplantation (72 cases were second transplantation, 5 cases were third transplantation). Especially for the second transplantation, we retrospectively analysed the clinical courses of grafted kidneys and sought the factors which might be related to the long term graft survival.
Results : Among second transplant patients, male were 52 cases, female were 20 cases. The mean age at retransplantation was 38.4±11 years. Living donor were 62 cases and cadaver donor were 10 cases. The mean duration between primary graft failure and second transplantation was 20.1±36 months. The 1 yr, 3 yr, 5 yr survival rates of the second grafts were 86.4%, 78%, 71% respectively, and it is not significantly inferior to that of total primary transplantation at our center. Multivariate analysis showed that the duration of the first graft survival and the postoperative recovery pattern significantly predicted graft survival in the second renal transplantation.
Conclusions : This study suggests retransplantation can be considered for patients who lost primary graft function. And the longer the duration of the first graft survival and the earlier the |
| Key Words:
Kidney transplantation, retransplantation, graft survival rate |
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