|
|
Sung Jin Kim, Kap Sung Jung, Kwang Ho Lee, Soo Hee Choi, Kyung Eun Lee, Sung Ho Lee, Kwang Je Lee, Sang Wook Kim, Tae Ho Kim, Chee Jeong Kim, Wang Seong Ryu |
|
Department of Internal Medicine, Hanyang University College of Medicine |
| 원저 : Prehypertension 성인에서 경동맥 내막-중막 두께의 변화 (Original Articles : The change in carotid intima-media thickness in prehypertensive adults) |
|
김성진, 정갑성, 이광호, 최수희, 이경은, 이성호, 이광제, 김상욱, 김태호, 김치정, 류왕성 |
|
|
|
|
|
|
| Abstract |
Background : Prehypertension is a precursor of clinical hypertension and tends to increase in
severity over time. Structural vascular changes have not been much investigated in adults with
prehypertension.
Methods
: We investigated the carotid intima-media thickness (IMT) in prehypertensive adults,
pharmacologically untreated, compared with normotensive and hypertensive patients. Mean and
maximum carotid IMT were obtained from six far walls of the common carotid, the bifurcation, and
the internal carotid artery on both sides of the neck with high-resolution B-mode ultrasonography.
Results
: Mean IMT was largest in the carotid bifurcation, followed by the common carotid and
the internal carotid artery in all groups. Hypertensives had higher mean IMT values at all locations
than normotensive controls. In prehypertensive adults, the mean and maximum IMT values were
significantly higher than in normotensive controls. In contrast, there was no significant difference in
the mean and maximum carotid IMT between prehypertensive adults and patients with stage 1
hypertension. The prevalence of plaques was 15.7% in prehypertensive adults, compared with 4.4%
in controls, 22.2% in stage 1 hypertensives, and 29.4% in stage 2 hypertensives.
Conclusion
: Prehypertensive adults had thicker mean carotid IMT than normotensive controls
and exhibited similarly abnormal carotid structure as the patients with stage 1 hypertension. These
results
suggest we need the continuous evaluation for early clinical detection and intervention of
prehypertension.(Korean J Med 70:165-171, 2006)
Key Words : Carotid artery, Prehypertension, Hypertension, Plaques |
| Key Words:
Carotid artery, Prehypertension, Hypertension, Plaques |
|
PDF Links
Full text via DOI
Download Citation
