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Korean J Med > Volume 88(6); 2015 > Article
The Korean Journal of Medicine 2015;88(6): 737-741.
강직성 척추염 환자에서 발생한 갑상선자극호르몬(TSH) 분비 뇌하수체 선종 1예
박지혜1, 이승근1, 박은경1, 구동완1, 김보현1, 김인주1, 김근태2
1부산대학교 의학전문대학원 내과학교실
2고신대학교 의과대학 내과학교실
A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
Ji-Heh Park1, Seung-Geun Lee1, Eun-Kyoung Park1, Dong-Wan Koo1, Bo-Hyun Kim1, In-Joo Kim1, Geun-Tae Kim2
1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
2Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
Corresponding Author: Seung-Geun Lee ,Tel: +82-51-240-7580, Fax: +82-51-241-7581, Email: sglee@pnuh.co.kr
Received: October 9, 2014;   Revised: November 6, 2014;   Accepted: December 1, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH α-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.
Keywords: Pituitary neoplasms; Thyrotropin; Spondylitis, Ankylosing
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