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Korean J Med > Volume 88(3); 2015 > Article
The Korean Journal of Medicine 2015;88(3): 330-334.
소장 폐쇄로 표현된 다발골수종의 골수 외 재발 1예
이명원1, 문지영1, 류혜원1, 최윤석1, 송익찬1, 김진만2, 조덕연1
1충남대학교 의과대학 내과학교실
2충남대학교 의과대학 병리학교실
Extramedullary Relapse of Multiple Myeloma Presenting as Mechanical Small Bowel Obstruction: A Case Report
Myung-Won Lee1, Ji-Young Moon1, Hea-Won Rhu1, Yoon-Seok Choi1, Ik-Chan Song1, Jin-Man Kim2, Deog-Yeon Jo1
1Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea
2Departments of Pathology, Chungnam National University School of Medicine, Daejeon, Korea
Corresponding Author: Deog-Yeon Jo ,Tel: +82-42-280-7162, Fax: +82-42-526-1871, Email: deogyeon@cnu.ac.kr
Received: April 4, 2014;   Revised: June 16, 2014;   Accepted: July 28, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Plasmacytoma in patients with multiple myeloma usually develops in the advanced stage of the disease. We report herein an atypical case of extramedullary relapse of multiple myeloma that presented as mechanical obstruction of the small bowel in a patient who had achieved complete remission after chemotherapy. A 75-year-old man was diagnosed with multiple myeloma 25 months previously and treated with a bortezomib-containing chemotherapy regimen. He presented for evaluation of abdominal pain. A circumferential mass resulting in mechanical ileus was observed by abdominal computed tomography. Biopsy after surgical resection confirmed the diagnosis of plasmacytoma. The patient was subsequently treated with thalidomide-containing chemotherapy, but he died of disease progression after 6 months. We suggest careful observation of unusual relapses of multiple myeloma in patients who have achieved complete remission after antimyeloma therapy.
Keywords: Plasmacytoma; Multiple myeloma; Intestinal obstruction
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