Korean J Med > Volume 88(2); 2015 > Article
The Korean Journal of Medicine 2015;88(2):224-230.
Published online February 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.2.224   
Two Cases of Primary Esophageal Diffuse Large B Cell Lymphoma: Therapeutic Considerations and a Literature Review
Ji hye Kim, Yun hwa Jung, In Sook Woo, Chi wha Han, Min woo Seo, Sang hoon Yoo, So young Ha
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
원발성 식도 미만성 거대 B세포 림프종 2예: 치료와 문헌적 고찰
김지혜, 정윤화, 우인숙, 한치화, 서민우, 유상훈, 하소영
가톨릭대학교 의과대학 내과학교실
Correspondence: 
Chi wha Han, Tel: +82-2-3779-2428, Fax: +82-2-780-3132, Email: cwhan@unitel.co.kr
Received: 27 January 2014   • Revised: 28 March 2014   • Accepted: 27 May 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Primary esophageal lymphoma is very rare, and most reported cases are histologically mucosa-associated lymphoid tissue lymphoma. Therefore, the principle treatment strategy for primary esophageal lymphoma focuses on local treatments, such as endoscopic mucosal resection or radiation therapy, but systemic chemotherapy plays the central role in the treatment of diffuse large B cell lymphoma (DLBCL). Generally, standard treatment for DLBCL is six or three cycles of R-CHOP chemotherapy followed by involved field radiation therapy according to stage. However, the optimal treatment strategy for primary esophageal DLBCL, and the role of additional radiation is not settled, due to a paucity of cases. Moreover, the clinical characteristics related to the etiology and natural course are also unknown. Here, we present two cases of primary esophageal DLBCL with a literature review.
Key Words: Esophagus; Diffuse large-cell lymphoma
주제어: 식도; 미만성 거대 세포 림프종


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