| Successful Salvage Treatment for Isolated Brain Parenchymal Relapse due to Diffuse Large B Cell Lymphoma |
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Seong Gyu Kim, Sung Hwa Bae, Hun Mo Ryoo |
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Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea |
| 미만성 거대 B세포 림프종의 중추신경계 재발 후 장기 생존한 2예 |
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김성규, 배성화, 류헌모 |
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대구가톨릭대학교 의과대학 내과학교실 |
Correspondence:
Sung Hwa Bae, Tel: +82-53-650-4388, Fax: +82-53-622-6062, Email: sunghwa@cu.ac.kr
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Received: 6 May 2014 • Revised: 16 June 2014 • Accepted: 8 July 2014 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Abstract |
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A central nervous system (CNS) relapse is a rare but mostly fatal complication in patients with diffuse large B cell lymphoma (DLBCL). CNS involvement can occur as an isolated event or can be combined with progression of systemic disease. There are limited data on treatment outcomes of patients with DLBCL and secondary CNS involvement. We report the clinical data, treatments, and outcomes of two DLBCL patients with isolated CNS relapses involving the brain parenchyma. Isolated CNS disease involving the brain parenchyma may be potentially treatable as the initial relapse site after complete remission from systemic treatment. |
| Key Words:
Diffuse large cell lymphoma; Central nervous system; Relapse |
| 주제어:
미만성 거대 세포 림프종; 중추신경계; 재발 |
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