Korean J Med > Volume 87(5); 2014 > Article
The Korean Journal of Medicine 2014;87(5):625-629.
Published online November 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.5.625   
Glucocorticoid Triggers an Attack of Periodic Hypokalemic Paralysis during Treatment for Diffuse Large B-cell Lymphoma
Kyung Sun Ha, Young Jae Park, Sung Soo Park, Joon Yub Lee, Ji Hyun Kim, Inae Jang, Jae Ho Byun
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
미만성 거대B세포 항암치료 중 유발된 주기적 저칼륨성 마비 1예
하경선, 박영재, 박성수, 이준엽, 김지현, 장인애, 변재호
가톨릭대학교 의과대학 내과학교실
Correspondence: 
Jae Ho Byun, Tel: +82-32-280-5857, Fax: +82-32-280-5987, Email: jhbyun37@catholic.ac.kr
Received: 20 November 2013   • Revised: 24 February 2014   • Accepted: 29 March 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Hypokalemic periodic paralysis is a rare disorder characterized by sudden onset of weakness and low serum potassium levels. We report a case provoked by combination chemotherapy including prednisolone. A 23-yr-man, diagnosed with diffuse large B-cell lymphoma, received chemotherapy. He developed significant weakness in upper and lower extremities during chemotherapy, and his serum potassium level was 1.7 mmol/L. Potassium replacement restored the weakness. Further workup revealed that prednisolone had provoked hypokalemic paralysis. As prednisolone triggered an attack of hypokalemic periodic paralysis, it should be administered with caution, particularly in patients with periodic paralysis.
Key Words: Hypokalemic periodic paralysis; Diffuse large B-cell lymphoma
주제어: 저칼륨성 마비; 미만성 거대B세포 림프종


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