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Korean J Med > Volume 87(3); 2014 > Article
The Korean Journal of Medicine 2014;87(3): 379-382.
루푸스 신염 환자에서 항인지질 항체와 연관된 감염 후 대칭적 말초 괴저
이재성1, 성지석1, 우용문1, 조영준1, 정범진1, 강한나2, 김수정3
1서울적십자병원 내과
2서울적십자병원 병리과
3서울대학교 의과대학 서울대학교병원 공공보건의료사업단
Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis
Jae Sung Lee1, Jee Seok Seong1, Yong Moon Woo1, Young Jun Cho1, Beom Jin Jeong1, Han Na Kang2, Su-Jung Kim3
1Departments of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea
2Departments of Pathology, Seoul Red Cross Hospital, Seoul, Korea
3Division of Public Health Medical Service, Seoul National University Hospital, Seoul University College of Medicine, Seoul, Korea
Corresponding Author: Su-Jung Kim ,Tel: +82-2-2072-0055, Fax: +82-2-2072-0374, Email: annie8012@naver.com
Received: December 3, 2013;   Revised: January 8, 2014;   Accepted: March 4, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidity associated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report a case of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipid antibodies in a patient with lupus nephritis.
Keywords: Antibodies; Antiphospholipid; Lupus nephritis; Gangrene; Thrombosis
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